MADRID (Reuters) – Spain’s PharmaMar said on Tuesday trials made in vitro and on animals showed its Plitidepsin drug had positive antiviral effects on the variants of COVID-19, including Omicron.
The results of Phase I trials have shown the drug, also known as Aplidin, had a powerful antiviral activity against all the variants in vitro and a distribution into the lungs of animals tested, resulting in a 99% reduction of viral load in the lungs, the company said.
The results of the trials were released in a paper published in the scientific journal Life Science Alliance, PharmaMar said.
The paper also reported positive effects of Phase I and II trials on patients.
“All data we have seen so far with Plitidepsin corroborate our initial hypothesis of its activity as antiviral,” PharmaMar’s Jose Maria Fernandez Sousa said in a statement.
The drug is being tested in final Phase III trials on patients.
Shares in PharmaMar rose 5.3% in early trading.
Plitidepsin is a drug developed by PharmaMar originally to treat cancer, but has an effect as an antiviral.
(Reporting by Inti Landauro, and Louise Heavens)
